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Management of Postherpetic Neuralgia in Stroke Patients: ALiterature Review

 黃雅鈴(Ya-Ling Huang);黃柏豪(Pai-Hao Huang)
Postherpetic neuralgia is the most common complication of herpes zoster. The pain may persist for years or for life, and may interfere with patient in multiple aspects such as sleep, mood, physical function and quality of life. The incidence of herpes zoster and postherpetic neuralgia as well as stroke both increase with age. Following herpes zoster, the risk of stroke is raised temporarily, hence the number of individuals concurrently having stroke and postherpetic neuralgia increases with age. Management of postherpetic neuralgia remains challenging. So far no cure existed for postherpetic neuralgia, only symptomatic treatment aimed to attenuate the severity and shorten the duration of the pain. Stroke patients are usually older with multiple comorbidities, taking polypharmacy, and are vulnerable to treatment-related adverse events. There is no consensus in the management of postherpetic neuralgia in stroke patients. The management mainly based on the established evidence in the general population. We reviewed the literature of the correlation between stroke and herpes zoster and of the management for postherpetic neuralgia, and discussed the management in stroke patients in this article.