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Ultrasound-guided Cryoneurolysis in Chronic and Acute Pain Management: A Brief Literature Review

 賈琬婷(Wan-Ting Chia);石明煌(Ming-Hwang Shyr)
A cryoneurolysis procedure for pain management involves freezing or cooling tips of needles, called cryoprobes, that are placed in precise locations closed to nerves. The targeted cryoablative therapy temperature was -60蚓 to -100蚓 resulting in a reversible injury (take 2-12 weeks to recover fully) to the peripheral sensory nerve providing a long lasting (multiple weeks to months) analgesic effect without damaging surrounding tissue. In the past decade, ultrasound has become a useful and efficient tool for interventional pain management. Cryoneurolysis can be safely applied percutaneously in precise location with ultrasound guidance. Although, in our society, some may not be so familiar with its use, it has been used for decades to treat a substantial number of patients with chronic intractable pain, in order to reduce pain, reduce analgesic dose, recover activity of daily livings, and finally to be discharged from the hospital. More recently, it was also advocated to be used in treating some acute postoperative pain as alternatives. In this brief review, we will discuss and focus on the ideas, working mechanisms, clinical applications in chronic and acute pain patient, contraindications and future implementations of ultrasound-guided cryoneurolysis.